STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
acnA1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)    
Predicted Functional Partners:
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.983
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.982
icd-2
Isocitrate dehydrogenase [NADP].
 
 0.978
BAV2733
Conserved hypothetical protein.
  
 
 0.958
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.922
icd
Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family.
  
 
 0.912
acnB
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
    
 0.910
acnA2
Aconitate hydratase; Also similar to BAV2732 (41.8 38d.), BAV2514 (40.9 id) and BAV0625 (44.6 38d).
  
  
 
0.908
acnA3
Putative lipoprotein (pseudogene); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
  
 
0.906
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.696
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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