cbpA protein (Bordetella avium) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

cbpA

Curved DNA-binding protein. (312 aa)

Predicted Functional Partners:

BAV0874

0.990

dnaK

0.962

htpG

0.927

grpE

0.926

hscA

0.915

BAV3119

0.882

groEL

0.794

ppiB

0.785

rplC

0.758

rplQ

0.745

Your Current Organism:

Bordetella avium

NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAV0874	cbpA	BAV0874	BAV0873	Conserved hypothetical protein.	Curved DNA-binding protein.	0.990
BAV3119	cbpA	BAV3119	BAV0873	Putative heat shock protein.	Curved DNA-binding protein.	0.882
BAV3119	groEL	BAV3119	BAV0579	Putative heat shock protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.848
BAV3119	grpE	BAV3119	BAV2718	Putative heat shock protein.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.919
BAV3119	htpG	BAV3119	BAV0447	Putative heat shock protein.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.934
BAV3119	ppiB	BAV3119	BAV2564	Putative heat shock protein.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.437
BAV3119	rplC	BAV3119	BAV0025	Putative heat shock protein.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.409
cbpA	BAV0874	BAV0873	BAV0874	Curved DNA-binding protein.	Conserved hypothetical protein.	0.990
cbpA	BAV3119	BAV0873	BAV3119	Curved DNA-binding protein.	Putative heat shock protein.	0.882
cbpA	dnaK	BAV0873	BAV2716	Curved DNA-binding protein.	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.962
cbpA	groEL	BAV0873	BAV0579	Curved DNA-binding protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.794
cbpA	grpE	BAV0873	BAV2718	Curved DNA-binding protein.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.926
cbpA	hscA	BAV0873	BAV1512	Curved DNA-binding protein.	Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.915
cbpA	htpG	BAV0873	BAV0447	Curved DNA-binding protein.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.927
cbpA	ppiB	BAV0873	BAV2564	Curved DNA-binding protein.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.785
cbpA	rplC	BAV0873	BAV0025	Curved DNA-binding protein.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.758
cbpA	rplQ	BAV0873	BAV0061	Curved DNA-binding protein.	50S ribosomal protein L17.	0.745
dnaK	cbpA	BAV2716	BAV0873	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Curved DNA-binding protein.	0.962
dnaK	groEL	BAV2716	BAV0579	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.968
dnaK	grpE	BAV2716	BAV2718	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.993