| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAV1500 | benE-2 | BAV1500 | BAV1501 | GntR-family transcriptional regulator. | Benzoate membrane transport protein. | 0.703 |
| benE-2 | BAV1500 | BAV1501 | BAV1500 | Benzoate membrane transport protein. | GntR-family transcriptional regulator. | 0.703 |
| benE-2 | bioF | BAV1501 | BAV2449 | Benzoate membrane transport protein. | 8-amino-7-oxononanoate synthase. | 0.595 |
| benE-2 | catC2 | BAV1501 | BAV0307 | Benzoate membrane transport protein. | Methylmuconolactone isomerase; Belongs to the muconolactone Delta-isomerase family. | 0.544 |
| benE-2 | dapA1 | BAV1501 | BAV0110 | Benzoate membrane transport protein. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.601 |
| benE-2 | dapA2 | BAV1501 | BAV2594 | Benzoate membrane transport protein. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.601 |
| benE-2 | gabD | BAV1501 | BAV0968 | Benzoate membrane transport protein. | Succinate-semialdehyde dehydrogenase [NADP+]. | 0.581 |
| benE-2 | gabD-2 | BAV1501 | BAV2549 | Benzoate membrane transport protein. | Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. | 0.581 |
| benE-2 | glyA | BAV1501 | BAV2961 | Benzoate membrane transport protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.617 |
| benE-2 | guaA | BAV1501 | BAV1568 | Benzoate membrane transport protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.735 |
| benE-2 | thiG | BAV1501 | BAV3069 | Benzoate membrane transport protein. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.581 |
| bioF | benE-2 | BAV2449 | BAV1501 | 8-amino-7-oxononanoate synthase. | Benzoate membrane transport protein. | 0.595 |
| bioF | dapA1 | BAV2449 | BAV0110 | 8-amino-7-oxononanoate synthase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.614 |
| bioF | dapA2 | BAV2449 | BAV2594 | 8-amino-7-oxononanoate synthase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.614 |
| bioF | gabD | BAV2449 | BAV0968 | 8-amino-7-oxononanoate synthase. | Succinate-semialdehyde dehydrogenase [NADP+]. | 0.620 |
| bioF | gabD-2 | BAV2449 | BAV2549 | 8-amino-7-oxononanoate synthase. | Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. | 0.620 |
| bioF | glyA | BAV2449 | BAV2961 | 8-amino-7-oxononanoate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.750 |
| bioF | guaA | BAV2449 | BAV1568 | 8-amino-7-oxononanoate synthase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.785 |
| bioF | thiG | BAV2449 | BAV3069 | 8-amino-7-oxononanoate synthase. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.629 |
| catC2 | benE-2 | BAV0307 | BAV1501 | Methylmuconolactone isomerase; Belongs to the muconolactone Delta-isomerase family. | Benzoate membrane transport protein. | 0.544 |