STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sphB1Autotransporter serine protease (pseudogene); Unassigned protein domain. (984 aa)    
Predicted Functional Partners:
fhaB
Filamentous hemagglutinin/adhesin.
 
 
 0.978
fhaC
Hemolysin activator protein; A related gene, hagA (BAVXXX) may function to export the B. avium hemagglutinin, HagB; an additional pair of fhaBC/hagAB genes occurs at BAVXXX.
 
  
 0.962
piuA
Hydroxamate-type ferrisiderophore receptor.
  
    0.948
BAV1551
Putative filamentous hemagglutinin/adhesin; Similar to fhaS and fhaL of B. bronchiseptica. It is also located at the same position as B. bronchiseptica fhaS.
 
 
 0.942
BAV0712
Adhesin.
 
 
 0.934
BAV0121
Putative filamentous surface protein; Similar to the N-terminus of fhaS in B. bronchiseptica.
  
 
 0.921
hagB2
Putative hemolysin/hemagglutin; Nearly identical copy of BAV2825, HagB, (96 38d.); no mutants isolated; similar to the N-terminal 1050 residues of the bordetellae FhaB.
  
 
 0.921
hagB1
Putative hemolysin/hemagglutin; HagB is essential for virulence as shown in labs of L. Temple and P. Orndorff; both hagA and hagB required for virulence and hemagglutination of guinea pig erythrocytes; Nearly identical copy of 2819, HagB2, (96 38d.); similar to the N-terminal 1050 residues of the bordetellae FhaB.
  
 
 0.921
BAV0164
Conserved hypothetical protein; Start codon not provided.
  
    0.893
fimC
Outer membrane fimbrial usher protein; Start codon not provided.
  
    0.750
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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