nagK protein (Bordetella avium) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nagK

Fumarylpyruvate hydrolase. (233 aa)

Predicted Functional Partners:

BAV2295

0.902

fahA

0.900

fumC

0.817

sdhA

0.810

nagL

0.809

sdhB

0.806

sdhD

0.805

fumA

0.802

sdhC

0.802

nagI

0.681

Your Current Organism:

Bordetella avium

NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAV2295	fahA	BAV2295	BAV0527	Putative hydrolase.	Fumarylacetoacetase.	0.900
BAV2295	fumA	BAV2295	BAV0711	Putative hydrolase.	Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.802
BAV2295	fumC	BAV2295	BAV0733	Putative hydrolase.	Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.817
BAV2295	nagK	BAV2295	BAV1783	Putative hydrolase.	Fumarylpyruvate hydrolase.	0.902
BAV2295	sdhA	BAV2295	BAV1184	Putative hydrolase.	Succinate dehydrogenase flavoprotein subunit; Start codon not provided; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.810
BAV2295	sdhB	BAV2295	BAV1185	Putative hydrolase.	Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.806
BAV2295	sdhC	BAV2295	BAV1182	Putative hydrolase.	Succinate dehydrogenase cytochrome b-556 subunit.	0.802
BAV2295	sdhD	BAV2295	BAV1183	Putative hydrolase.	Succinate dehydrogenase hydrophobic membrane anchor subunit.	0.805
fahA	BAV2295	BAV0527	BAV2295	Fumarylacetoacetase.	Putative hydrolase.	0.900
fahA	fumA	BAV0527	BAV0711	Fumarylacetoacetase.	Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.801
fahA	fumC	BAV0527	BAV0733	Fumarylacetoacetase.	Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.817
fahA	nagK	BAV0527	BAV1783	Fumarylacetoacetase.	Fumarylpyruvate hydrolase.	0.900
fahA	nagL	BAV0527	BAV1784	Fumarylacetoacetase.	Maleylpyruvate isomerase (glutathione S-transferase).	0.971
fahA	sdhA	BAV0527	BAV1184	Fumarylacetoacetase.	Succinate dehydrogenase flavoprotein subunit; Start codon not provided; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.810
fahA	sdhB	BAV0527	BAV1185	Fumarylacetoacetase.	Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.806
fahA	sdhC	BAV0527	BAV1182	Fumarylacetoacetase.	Succinate dehydrogenase cytochrome b-556 subunit.	0.802
fahA	sdhD	BAV0527	BAV1183	Fumarylacetoacetase.	Succinate dehydrogenase hydrophobic membrane anchor subunit.	0.805
fumA	BAV2295	BAV0711	BAV2295	Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Putative hydrolase.	0.802
fumA	fahA	BAV0711	BAV0527	Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Fumarylacetoacetase.	0.801
fumA	fumC	BAV0711	BAV0733	Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.973