STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (358 aa)    
Predicted Functional Partners:
leuD2
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.998
leuC1
3-isopropylmalate dehydratase large subunit.
 0.997
leuC2
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.997
leuD1
3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family.
 
 0.993
ilvH
Acetolactate synthase isozyme III small subunit.
 
 0.981
ilvI1
Acetolactate synthase isozyme III large subunit; Also similar to BAV3387 (46.528 38d).
 
 0.974
ilvI2
Acetolactate synthase isozyme III large subunit; Also similar to BAV2673 (46.528 38d).
 
 0.969
BAV0961
Putative acetolactate synthase large subunit; Start codon not provided; Belongs to the TPP enzyme family.
 
 0.942
tdcB-2
Threonine dehydratase catabolic.
 
 
 0.942
ilvG
Acetolactate synthase synthase isozyme II large subunit; Also similar to BAV0902 (52.585 38d.); Belongs to the TPP enzyme family.
 
 0.940
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.