STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metE-25-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (766 aa)    
Predicted Functional Partners:
metH
Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Start codon not provided.
  
 
 0.977
metK
S-adenosylmethionine synthetase; Start codon not provided; Belongs to the AdoMet synthase family.
  
 0.966
acyH
Adenosylhomocysteinase; Start codon not provided.
  
 
 0.959
metC
Cystathionine beta-lyase; Previously sequenced as Bordetella avium cystathionine beta-lyase metC SWALL:METC_BORAV (SWALL:Q07703) (395 aa).
  
 
 0.958
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.911
cysD1
O-acetylhomoserine sulfhydrylase; Almost identical to BAV2830 (98.8 38d).
  
 
 0.911
BAV2122
Cys/Met metabolism PLP-dependent enzyme.
  
 
 0.911
cysD2
O-acetylhomoserine sulfhydrylase; Almost identical to BAV0639 (98.8 38d).
  
 
 0.911
tyrB
Aromatic-amino-acid aminotransferase.
     
 0.905
metF
5,10-methylenetetrahydrofolate reductase; Deleted EC_number 1.7.99.5; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.901
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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