typA protein (Bordetella avium) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

typA

GTP-binding protein. (606 aa)

Predicted Functional Partners:

truB

0.859

rimP

0.814

infB

0.795

rbfA

0.750

nusA

0.749

guaA

0.737

engD

0.629

rpsI

0.618

gltB

0.602

uup

0.588

Your Current Organism:

Bordetella avium

NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
engD	gltB	BAV0541	BAV3291	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	Glutamate synthase [NADPH] large chain precursor.	0.462
engD	guaA	BAV0541	BAV1568	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.699
engD	infB	BAV0541	BAV2394	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.541
engD	rpsI	BAV0541	BAV2969	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.570
engD	truB	BAV0541	BAV2392	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.501
engD	typA	BAV0541	BAV2391	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	GTP-binding protein.	0.629
gltB	engD	BAV3291	BAV0541	Glutamate synthase [NADPH] large chain precursor.	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.462
gltB	guaA	BAV3291	BAV1568	Glutamate synthase [NADPH] large chain precursor.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.744
gltB	infB	BAV3291	BAV2394	Glutamate synthase [NADPH] large chain precursor.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.511
gltB	typA	BAV3291	BAV2391	Glutamate synthase [NADPH] large chain precursor.	GTP-binding protein.	0.602
guaA	engD	BAV1568	BAV0541	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.699
guaA	gltB	BAV1568	BAV3291	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase [NADPH] large chain precursor.	0.744
guaA	infB	BAV1568	BAV2394	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.683
guaA	nusA	BAV1568	BAV2395	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Transcription elongation protein (N utilization substance protein); Participates in both transcription termination and antitermination.	0.531
guaA	rpsI	BAV1568	BAV2969	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.595
guaA	truB	BAV1568	BAV2392	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.908
guaA	typA	BAV1568	BAV2391	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein.	0.737
infB	engD	BAV2394	BAV0541	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.541
infB	gltB	BAV2394	BAV3291	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	Glutamate synthase [NADPH] large chain precursor.	0.511
infB	guaA	BAV2394	BAV1568	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.683