alkA protein (Bordetella avium) - STRING interaction network

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Score

alkA

DNA-3-methyladenine glycosylase. (214 aa)

Predicted Functional Partners:

ogt

0.922

BAV2215

0.917

cysS

0.797

accA

0.706

mesJ

0.683

BAV2563

0.614

polA

0.573

BAV2217

0.555

ada

0.555

ask

0.520

Your Current Organism:

Bordetella avium

NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAV2215	BAV2217	BAV2215	BAV2217	DNA-3-methyladenine glycosylase.	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	0.894
BAV2215	ada	BAV2215	BAV3120	DNA-3-methyladenine glycosylase.	Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.).	0.555
BAV2215	alkA	BAV2215	BAV2561	DNA-3-methyladenine glycosylase.	DNA-3-methyladenine glycosylase.	0.917
BAV2215	ogt	BAV2215	BAV3160	DNA-3-methyladenine glycosylase.	methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.	0.700
BAV2215	polA	BAV2215	BAV2388	DNA-3-methyladenine glycosylase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.573
BAV2217	BAV2215	BAV2217	BAV2215	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	DNA-3-methyladenine glycosylase.	0.894
BAV2217	ada	BAV2217	BAV3120	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.).	0.739
BAV2217	alkA	BAV2217	BAV2561	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	DNA-3-methyladenine glycosylase.	0.555
BAV2217	ogt	BAV2217	BAV3160	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.	0.464
BAV2217	polA	BAV2217	BAV2388	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.642
BAV2563	accA	BAV2563	BAV2560	Putative exported protein; Start codon not provided.	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.425
BAV2563	alkA	BAV2563	BAV2561	Putative exported protein; Start codon not provided.	DNA-3-methyladenine glycosylase.	0.614
BAV2563	cysS	BAV2563	BAV2562	Putative exported protein; Start codon not provided.	cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.531
accA	BAV2563	BAV2560	BAV2563	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Putative exported protein; Start codon not provided.	0.425
accA	alkA	BAV2560	BAV2561	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	DNA-3-methyladenine glycosylase.	0.706
accA	ask	BAV2560	BAV2558	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Aspartokinase; Belongs to the aspartokinase family.	0.629
accA	cysS	BAV2560	BAV2562	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.729
accA	mesJ	BAV2560	BAV2559	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	tRNAIle-lysidine synthetase (putative cell cycle protein); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.	0.825
ada	BAV2215	BAV3120	BAV2215	Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.).	DNA-3-methyladenine glycosylase.	0.555
ada	BAV2217	BAV3120	BAV2217	Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.).	Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.).	0.739