STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnA4Aconitate hydratase 2; Also similar to BAV1017 (41.9 38d.), BAV2514 (43.721 38d) and BAV0625 (45.345 0d). (869 aa)    
Predicted Functional Partners:
BAV2733
Conserved hypothetical protein.
 
 
 0.995
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.989
BAV2731
GntR-family transcriptional regulator.
  
    0.794
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.781
icd-2
Isocitrate dehydrogenase [NADP].
  
 0.764
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.730
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.696
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 0.668
phbB-2
acetoacetyl-CoA reductase; Start codon not provided; Similar to N-terminal half of Escherichia coli probable 3-hydroxybutyryl-coa dehydrogenase paaH SWALL:PAAH_ECOLI (SWALL:P76083) (475 aa) fasta scores: E(): 5.4e-15, 30.79 38d in 328 aa.
   
 0.615
fumA
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.597
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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