STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hagA1Putative hemolysin/hemagglutin accessory protein; Virulence locus as shown in labs of L. Temple and P. Orndorff; both hagA and hagB required for virulence and hemagglutination of guinea pig erythrocytes; Also highly similar to BAV2818, HagA2, (53.4 38d). (537 aa)    
Predicted Functional Partners:
fhaC
Hemolysin activator protein; A related gene, hagA (BAVXXX) may function to export the B. avium hemagglutinin, HagB; an additional pair of fhaBC/hagAB genes occurs at BAVXXX.
     
 0.972
hagB2
Putative hemolysin/hemagglutin; Nearly identical copy of BAV2825, HagB, (96 38d.); no mutants isolated; similar to the N-terminal 1050 residues of the bordetellae FhaB.
  
 0.972
hagA2
Putative hemolysin/hemagglutin accessory protein; Higly similar to BAV2824, HagA (53.4 38d). Also similar to the bordetellae FhaC.
    
 
0.918
BAV0121
Putative filamentous surface protein; Similar to the N-terminus of fhaS in B. bronchiseptica.
  
 0.917
BAV0712
Adhesin.
  
 0.917
BAV1551
Putative filamentous hemagglutinin/adhesin; Similar to fhaS and fhaL of B. bronchiseptica. It is also located at the same position as B. bronchiseptica fhaS.
  
 0.917
fhaB
Filamentous hemagglutinin/adhesin.
  
 0.917
hagB1
Putative hemolysin/hemagglutin; HagB is essential for virulence as shown in labs of L. Temple and P. Orndorff; both hagA and hagB required for virulence and hemagglutination of guinea pig erythrocytes; Nearly identical copy of 2819, HagB2, (96 38d.); similar to the N-terminal 1050 residues of the bordetellae FhaB.
  
 0.917
BAV1945
Putative adhesin.
   
  
 0.627
BAV0535
Putative outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
      
 0.594
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.