STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hagB1Putative hemolysin/hemagglutin; HagB is essential for virulence as shown in labs of L. Temple and P. Orndorff; both hagA and hagB required for virulence and hemagglutination of guinea pig erythrocytes; Nearly identical copy of 2819, HagB2, (96 38d.); similar to the N-terminal 1050 residues of the bordetellae FhaB. (1355 aa)    
Predicted Functional Partners:
fhaC
Hemolysin activator protein; A related gene, hagA (BAVXXX) may function to export the B. avium hemagglutinin, HagB; an additional pair of fhaBC/hagAB genes occurs at BAVXXX.
 
 0.978
sphB1
Autotransporter serine protease (pseudogene); Unassigned protein domain.
  
 
 0.922
hagA2
Putative hemolysin/hemagglutin accessory protein; Higly similar to BAV2824, HagA (53.4 38d). Also similar to the bordetellae FhaC.
  
 0.917
hagA1
Putative hemolysin/hemagglutin accessory protein; Virulence locus as shown in labs of L. Temple and P. Orndorff; both hagA and hagB required for virulence and hemagglutination of guinea pig erythrocytes; Also highly similar to BAV2818, HagA2, (53.4 38d).
  
 0.917
BAV0850
Putative membrane protein.
  
    0.601
wlbJK
Putative membrane protein.
  
  
 0.514
BAV1283
Putative phage methyltransferase.
  
    0.493
BAV2426
Putative exported protein.
  
     0.437
BAV1777
One of 11 fimbrial subunits.
  
    0.421
fhaD
Fimbrial chaperone protein.
  
  
 0.409
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.