STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bhuROuter membrane TonB-dependent heme receptor. (824 aa)    
Predicted Functional Partners:
hurR
Heme uptake transmembrane sensor.
 
  
 0.861
bhuS
Putative heme degradase.
 
  
 0.825
bhuV
Hemin ABC transporter, ATP-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
  
 0.753
bhuT
Hemin ABC transporter, substrate-binding protein.
 
  
 0.753
hurI
Heme uptake RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
  
 0.735
bhuU
Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.726
BAV2106
Putative transmembrane sensor protein; Start codon not provided.
 
  
 0.650
BAV3379
Putative membrane protein.
  
     0.638
tonB
Siderophore-mediated iron transport protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.623
BAV3003
Putative membrane protein; Start codon not provided.
  
 
 0.623
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.