STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
selDSelenide,water dikinase (TCA); Synthesizes selenophosphate from selenide and ATP. (349 aa)    
Predicted Functional Partners:
selA
selenocysteinyl-tRNA(SeC) synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.992
selB
Selenocysteine-specific elongation factor.
 
   
 0.928
trxB
Thioredoxin reductase.
     
 0.912
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 
 0.898
fdhE
Formate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
   
 0.795
fdnG
Formate dehydrogenase, major subunit; The active-site selenocysteine, residue 197, is encoded by an opal stop codon.
 
   
 0.789
fdnH
Nformate dehydrogenase, iron-sulfur subunit.
 
   
 0.765
fdnI
Formate dehydrogenase, cytochrome b556.
 
   
 0.704
fdsC
Formate dehydrogenase associated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
     
 0.445
BAV2355
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
     
 0.436
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.