| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ampD | ampG | BAV0449 | BAV3185 | N-acetylmuramoyl-L-alanine amidase. | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 0.527 |
| ampD | anmK | BAV0449 | BAV2965 | N-acetylmuramoyl-L-alanine amidase. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.585 |
| ampD | murE | BAV0449 | BAV2883 | N-acetylmuramoyl-L-alanine amidase. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.424 |
| ampD | nagZ | BAV0449 | BAV2457 | N-acetylmuramoyl-L-alanine amidase. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.613 |
| ampG | ampD | BAV3185 | BAV0449 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | N-acetylmuramoyl-L-alanine amidase. | 0.527 |
| ampG | anmK | BAV3185 | BAV2965 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.538 |
| ampG | aroQ | BAV3185 | BAV2998 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.402 |
| ampG | metW | BAV3185 | BAV3186 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | Putative methionine biosynthesis protein. | 0.620 |
| ampG | metX | BAV3185 | BAV3187 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | Homoserine-ortho-acyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.636 |
| ampG | murE | BAV3185 | BAV2883 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.432 |
| ampG | nagZ | BAV3185 | BAV2457 | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.575 |
| anmK | ampD | BAV2965 | BAV0449 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramoyl-L-alanine amidase. | 0.585 |
| anmK | ampG | BAV2965 | BAV3185 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 0.538 |
| anmK | murE | BAV2965 | BAV2883 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.403 |
| anmK | nagZ | BAV2965 | BAV2457 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.597 |
| aroQ | ampG | BAV2998 | BAV3185 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 0.402 |
| metW | ampG | BAV3186 | BAV3185 | Putative methionine biosynthesis protein. | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 0.620 |
| metW | metX | BAV3186 | BAV3187 | Putative methionine biosynthesis protein. | Homoserine-ortho-acyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.998 |
| metX | ampG | BAV3187 | BAV3185 | Homoserine-ortho-acyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | Integral membrane signal transducer protein (peptidoglycan recycling); Start codon not provided. | 0.636 |
| metX | metW | BAV3187 | BAV3186 | Homoserine-ortho-acyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | Putative methionine biosynthesis protein. | 0.998 |