STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLAC_08615Peptidase M66 domain-containing protein. (771 aa)    
Predicted Functional Partners:
DLAC_06381
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.594
DLAC_02699
GTP-binding nuclear protein Ran.
    
 0.594
DLAC_07814
Pleckstrin (PH) domain-containing protein.
   
 0.506
DLAC_05125
Leucine-rich repeat-containing protein (LRR).
   
 0.506
DLAC_09525
RNA_lig_T4_1 domain-containing protein.
    
 0.499
DLAC_09442
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.452
DLAC_09924
Diphthamide biosynthesis protein 3.
    
 
 0.426
DLAC_07714
Histone H2A domain-containing protein; Belongs to the histone H2A family.
    
  0.400
DLAC_01600
Histone H2A; Belongs to the histone H2A family.
    
  0.400
Your Current Organism:
Tieghemostelium lacteum
NCBI taxonomy Id: 361077
Other names: Dictyostelium lacteum, T. lacteum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.