STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLAC_05750Villin. (814 aa)    
Predicted Functional Partners:
DLAC_03034
Small GTPase.
    
 0.892
DLAC_04210
Uncharacterized protein.
    
 0.859
DLAC_08700
Serine/threonine-protein kinase PLK.
    
 0.831
DLAC_06016
DUF1740 family protein.
    
 0.783
DLAC_07814
Pleckstrin (PH) domain-containing protein.
    
 0.737
DLAC_05125
Leucine-rich repeat-containing protein (LRR).
    
 0.737
DLAC_07926
DUF667 domain-containing protein.
    
   0.723
DLAC_05237
Cytoplasmic dynein heavy chain.
    
 
 0.717
DLAC_08161
DNA-binding HORMA domain-containing protein.
    
 
 0.664
DLAC_00389
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
   
   0.638
Your Current Organism:
Tieghemostelium lacteum
NCBI taxonomy Id: 361077
Other names: Dictyostelium lacteum, T. lacteum
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