STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLAC_05155Putative mediator complex subunit 25. (1284 aa)    
Predicted Functional Partners:
DLAC_06599
ATP-dependent RNA helicase.
    
 0.626
DLAC_06989
Actin related protein 5; Belongs to the actin family.
    
 0.616
DLAC_06482
DDT domain-containing protein.
   
 0.615
DLAC_08650
RuvB-like helicase; Belongs to the RuvB family.
    
 0.612
DLAC_02409
RNA polymerase II core subunit.
    
 0.600
DLAC_09138
RNA polymerase II complex component.
   
 
 0.582
DLAC_07977
YL1_C domain-containing protein.
    
 0.577
DLAC_09478
WD-40 repeat-containing protein.
    
 0.575
DLAC_09442
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.574
DLAC_08700
Serine/threonine-protein kinase PLK.
   
 0.573
Your Current Organism:
Tieghemostelium lacteum
NCBI taxonomy Id: 361077
Other names: Dictyostelium lacteum, T. lacteum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.