Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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surE5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.952
pyrH
Uridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.947
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.942
ALE17032.1
Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.
 
  
  0.924
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.922
ALE16914.1
NADH pyrophosphatase.
  
 
  0.921
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.921
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
  0.920
cmk
Cytidylate kinase.
    
 0.919
purH
IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase.
     
 0.918
Your Current Organism:
Altererythrobacter epoxidivorans
NCBI taxonomy Id: 361183
Other names: A. epoxidivorans, Altererythrobacter epoxidivorans Kwon et al. 2007, JCM 13815, KCCM 42314, strain JCS350
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