node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDC04346.1 | menD | SAMN05421663_101238 | SAMN05421663_101660 | O-succinylbenzoate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.552 |
SDC04346.1 | menE | SAMN05421663_101238 | SAMN05421663_101663 | O-succinylbenzoate synthase. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.569 |
SDC04346.1 | menH | SAMN05421663_101238 | SAMN05421663_101661 | O-succinylbenzoate synthase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.401 |
SDC20590.1 | SDC20679.1 | SAMN05421663_101657 | SAMN05421663_101659 | Uncharacterized domain 1-containing protein. | Menaquinone-specific isochorismate synthase. | 0.657 |
SDC20590.1 | menA | SAMN05421663_101657 | SAMN05421663_101658 | Uncharacterized domain 1-containing protein. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.877 |
SDC20590.1 | menB | SAMN05421663_101657 | SAMN05421663_101662 | Uncharacterized domain 1-containing protein. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.921 |
SDC20590.1 | menC | SAMN05421663_101657 | SAMN05421663_101664 | Uncharacterized domain 1-containing protein. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.434 |
SDC20590.1 | menD | SAMN05421663_101657 | SAMN05421663_101660 | Uncharacterized domain 1-containing protein. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.670 |
SDC20590.1 | menE | SAMN05421663_101657 | SAMN05421663_101663 | Uncharacterized domain 1-containing protein. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.656 |
SDC20590.1 | menH | SAMN05421663_101657 | SAMN05421663_101661 | Uncharacterized domain 1-containing protein. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.462 |
SDC20679.1 | SDC20590.1 | SAMN05421663_101659 | SAMN05421663_101657 | Menaquinone-specific isochorismate synthase. | Uncharacterized domain 1-containing protein. | 0.657 |
SDC20679.1 | SDC20969.1 | SAMN05421663_101659 | SAMN05421663_101665 | Menaquinone-specific isochorismate synthase. | Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family. | 0.531 |
SDC20679.1 | menA | SAMN05421663_101659 | SAMN05421663_101658 | Menaquinone-specific isochorismate synthase. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.855 |
SDC20679.1 | menB | SAMN05421663_101659 | SAMN05421663_101662 | Menaquinone-specific isochorismate synthase. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.953 |
SDC20679.1 | menC | SAMN05421663_101659 | SAMN05421663_101664 | Menaquinone-specific isochorismate synthase. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.788 |
SDC20679.1 | menD | SAMN05421663_101659 | SAMN05421663_101660 | Menaquinone-specific isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.998 |
SDC20679.1 | menE | SAMN05421663_101659 | SAMN05421663_101663 | Menaquinone-specific isochorismate synthase. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.835 |
SDC20679.1 | menH | SAMN05421663_101659 | SAMN05421663_101661 | Menaquinone-specific isochorismate synthase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.958 |
SDC20679.1 | trpE | SAMN05421663_101659 | SAMN05421663_101110 | Menaquinone-specific isochorismate synthase. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.684 |
SDC20969.1 | SDC20679.1 | SAMN05421663_101665 | SAMN05421663_101659 | Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family. | Menaquinone-specific isochorismate synthase. | 0.531 |