STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJF63836.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.997
hutU-2
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.997
hutI
Imidazolonepropionase; Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.967
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.924
hutH
Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.902
egtD
histidyl-tRNA synthetase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
     
  0.900
AJF64544.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.743
AJF68817.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.743
AJF63837.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.675
AJF65523.1
N-formimino-L-glutamate deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.625
Your Current Organism:
Streptomyces vietnamensis
NCBI taxonomy Id: 362257
Other names: CCTCC M 205143, CCTCC:M:205143, IAM 15340, JCM 21785, S. vietnamensis, Streptomyces vietnamensis Zhu et al. 2007, strain GIMV4.0001
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