STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (816 aa)    
Predicted Functional Partners:
RC62_1710
Single-stranded DNA-binding protein.
  
 
 
 0.855
RC62_4556
Single-stranded DNA-binding protein.
  
 
 
 0.838
RC62_1647
DUF3127 domain containing protein.
    
 
 0.748
RC62_2373
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
    0.747
pheT
Phenylalanine-tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.738
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
    0.711
RC62_4268
Single-stranded-DNA-specific exonuclease RecJ.
 
     0.689
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
     0.685
RC62_3130
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 0.679
RC62_2398
Putative ribonuclease BN.
 
     0.653
Your Current Organism:
Flavobacterium aquidurense
NCBI taxonomy Id: 362413
Other names: CIP 109242, DSM 18293, F. aquidurense, Flavobacterium aquidurense Cousin et al. 2007 emend. Kim et al. 2014, Flavobacterium aquidurense Cousin et al. 2007 emend. Loch and Faisal 2014, Flavobacterium sp. WB-1.1.56, Flavobacterium sp. WB1.1-14, Flavobacterium sp. WB1.1-4, Flavobacterium sp. WB1.1-57, Flavobacterium sp. WB1.1-63, WB 1.1-56
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