Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mmsBCOG2084 [I] 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (287 aa)    
Predicted Functional Partners:
fba
COG0191 [G] Fructose/tagatose bisphosphate aldolase.
 
  
 0.916
pta
Phosphate acetyltransferase; COG0280 [C] Phosphotransacetylase.
    
  0.800
LSL_0544
Hypothetical protein; COG1694 [R] Predicted pyrophosphatase.
      0.657
rfaG
COG0463 [M] Glycosyltransferases involved in cell wall biogenesis.
       0.526
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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