STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0021COG4975 [G] Putative glucose uptake permease. (288 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; COG1925 [G] Phosphotransferase system, HPr-related proteins.
      
 0.706
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
  
   
 0.662
pstS
Phosphate-binding protein; COG0226 [P] ABC-type phosphate transport system, periplasmic component.
      
 0.574
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 [E] Methionine synthase II (cobalamin-independent).
      
 0.505
LSL_0020
Transcriptional regulator, TetR family; COG0583 [K] Transcriptional regulator.
       0.503
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
   
 0.473
LSL_0022
Hypothetical membrane spanning protein; COG0011 [S] Uncharacterized conserved protein.
       0.430
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
      
 0.418
LSL_0023
Hypothetical protein.
       0.413
LSL_1061
Polar amino acid ABC transporter, substrate binding protein; COG0834 [ET] ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.
      
 0.400
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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