Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LSL_0034Hydrolase, HAD superfamily; COG0561 [R] Predicted hydrolases of the HAD superfamily. (271 aa)    
Predicted Functional Partners:
LSL_1702
Hydrolase, HAD superfamily; COG0561 [R] Predicted hydrolases of the HAD superfamily.
  
     0.774
LSL_0338
Hydrolase; COG1078 [R] HD superfamily phosphohydrolases.
    
 0.600
LSL_0032
COG1132 [V] ABC-type multidrug transport system, ATPase and permease components.
       0.515
LSL_0033
Multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein; COG1132 [V] ABC-type multidrug transport system, ATPase and permease components.
       0.515
LSL_0031
Transcriptional regulator, MarR family; COG0583 [K] Transcriptional regulator.
  
    0.514
LSL_0035
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
     
 0.459
LSL_0036
Two-component sensor kinase yycG; COG0642 [T] Signal transduction histidine kinase.
  
    0.418
LSL_0037
Hypothetical membrane spanning protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.411
LSL_0038
COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.402
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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