STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0070COG2738 [R] Predicted Zn-dependent protease. (217 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
      
 0.700
LSL_0071
N-acetylglucosaminyltransferase; COG0463 [M] Glycosyltransferases involved in cell wall biogenesis.
       0.686
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.617
LSL_0231
Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
  
     0.605
LSL_0362
COG2404 [R] Predicted phosphohydrolase (DHH superfamily).
  
     0.572
ktrA
Potassium uptake protein; COG0569 [P] K+ transport systems, NAD-binding component.
       0.559
LSL_0335
Hypothetical secreted protein.
  
     0.545
LSL_0913
Putative acyltransferases and hydrolases with the alpha/beta hydrolase fold; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
 
     0.529
ktrB
Potassium uptake protein ktrB; COG0168 [P] Trk-type K+ transport systems, membrane components.
       0.520
gshA
Glutamate--cysteine ligase; COG2918 [H] Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family.
  
     0.511
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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