Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0070COG2738 [R] Predicted Zn-dependent protease. (217 aa)    
Predicted Functional Partners:
LSL_0071
N-acetylglucosaminyltransferase; COG0463 [M] Glycosyltransferases involved in cell wall biogenesis.
       0.686
LSL_0231
Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
  
     0.605
LSL_0362
COG2404 [R] Predicted phosphohydrolase (DHH superfamily).
  
     0.572
ktrA
Potassium uptake protein; COG0569 [P] K+ transport systems, NAD-binding component.
       0.559
LSL_0335
Hypothetical secreted protein.
  
     0.545
LSL_0913
Putative acyltransferases and hydrolases with the alpha/beta hydrolase fold; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
  
     0.529
ktrB
Potassium uptake protein ktrB; COG0168 [P] Trk-type K+ transport systems, membrane components.
       0.520
gshA
Glutamate--cysteine ligase; COG2918 [H] Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family.
  
     0.511
LSL_0334
Hypothetical secreted protein.
  
     0.490
LSL_1272
COG0344 [S] Predicted membrane protein.
  
     0.489
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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