Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0083COG2197 [TK] Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (218 aa)    
Predicted Functional Partners:
baeS
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
 
 0.998
LSL_0082
Putative sugar-binding protein; COG1653 [G] ABC-type sugar transport system, periplasmic component.
 
  
 0.957
rbsB
D-ribose-binding protein; COG1653 [G] ABC-type sugar transport system, periplasmic component.
 
  
 0.954
LSL_0205
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.690
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
      
 0.608
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
      
 0.608
LSL_0615
16S rRNA m(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.605
baeS-3
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
  
 
 0.594
LSL_0081
COG1811 [R] Uncharacterized membrane protein, possible Na+ channel or pump.
       0.471
manX
PTS system, mannose-specific IIAB component; COG2893 [G] Phosphotransferase system, mannose/fructose-specific component IIA.
       0.451
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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