Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rbsBD-ribose-binding protein; COG1653 [G] ABC-type sugar transport system, periplasmic component. (330 aa)    
Predicted Functional Partners:
LSL_0082
Putative sugar-binding protein; COG1653 [G] ABC-type sugar transport system, periplasmic component.
 
  
 0.971
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.963
baeS
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
 
    0.955
LSL_0083
COG2197 [TK] Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
  
 0.954
baeS-3
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
    
 
 0.875
fruA
COG1299 [G] Phosphotransferase system, fructose-specific IIC component.
     
 0.628
malR
Maltose operon transcriptional repressor; COG1522 [K] Transcriptional regulators.
 
  
 0.592
manX
PTS system, mannose-specific IIAB component; COG2893 [G] Phosphotransferase system, mannose/fructose-specific component IIA.
     
 0.584
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.484
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.484
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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