| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LSL_0471 | dnaJ | LSL_0471 | LSL_0579 | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.428 |
| LSL_0471 | glpF | LSL_0471 | LSL_0112 | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.482 |
| LSL_0616 | dnaJ | LSL_0616 | LSL_0579 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.734 |
| LSL_0616 | glpF | LSL_0616 | LSL_0112 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.482 |
| dnaJ | LSL_0471 | LSL_0579 | LSL_0471 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | 0.428 |
| dnaJ | LSL_0616 | LSL_0579 | LSL_0616 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | 0.734 |
| dnaJ | glpF | LSL_0579 | LSL_0112 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.544 |
| dnaJ | glpK | LSL_0579 | LSL_0110 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.530 |
| fruA | glpF | LSL_0165 | LSL_0112 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.621 |
| fruA | glpK | LSL_0165 | LSL_0110 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.677 |
| fruA | glpO | LSL_0165 | LSL_0111 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | Alpha-glycerophosphate oxidase; COG0240 [C] Glycerol-3-phosphate dehydrogenase. | 0.500 |
| glpF | LSL_0471 | LSL_0112 | LSL_0471 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | 0.482 |
| glpF | LSL_0616 | LSL_0112 | LSL_0616 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | 0.482 |
| glpF | dnaJ | LSL_0112 | LSL_0579 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.544 |
| glpF | fruA | LSL_0112 | LSL_0165 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | 0.621 |
| glpF | glpK | LSL_0112 | LSL_0110 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.903 |
| glpF | glpO | LSL_0112 | LSL_0111 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Alpha-glycerophosphate oxidase; COG0240 [C] Glycerol-3-phosphate dehydrogenase. | 0.886 |
| glpF | potA | LSL_0112 | LSL_0113 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Spermidine/putrescine transport ATP-binding protein potA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.504 |
| glpF | potB | LSL_0112 | LSL_0114 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | COG1176 [E] ABC-type spermidine/putrescine transport system, permease component I. | 0.491 |
| glpF | potC | LSL_0112 | LSL_0115 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | COG1177 [E] ABC-type spermidine/putrescine transport system, permease component II. | 0.480 |
