Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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potASpermidine/putrescine transport ATP-binding protein potA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (362 aa)    
Predicted Functional Partners:
potB
COG1176 [E] ABC-type spermidine/putrescine transport system, permease component I.
 0.999
potC
COG1177 [E] ABC-type spermidine/putrescine transport system, permease component II.
 
 0.999
potD
COG0687 [E] Spermidine/putrescine-binding periplasmic protein.
 0.999
cydC
Transport ATP-binding protein; COG4987 [CO] ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.
 
     
0.864
cydD
Transport ATP-binding protein; COG4988 [CO] ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.
 
     
0.857
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
     
 0.772
oppC
COG0601 [EP] ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.
      0.737
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.722
cbiQ
Cobalt transport permease protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
  
 0.635
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.622
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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