Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0128COG1791 [S] Uncharacterized conserved protein, contains double-stranded beta-helix domain. (136 aa)    
Predicted Functional Partners:
fldA
Flavodoxin; COG0716 [C] Flavodoxins.
 
     0.871
LSL_0126
CAAX amino terminal protease family; COG1266 [R] Predicted metal-dependent membrane protease.
       0.508
sir2
SIR2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
    0.503
LSL_1263
Transcriptional regulator, GntR family; COG1522 [K] Transcriptional regulators.
  
    0.502
LSL_1508
Transcription regulator, GntR family; COG1522 [K] Transcriptional regulators.
  
    0.502
treR
Trehalose operon transcriptional repressor; COG1522 [K] Transcriptional regulators.
  
    0.502
LSL_1725
Hypothetical protein; COG0716 [C] Flavodoxins.
 
     0.432
guaA-3
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.431
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
    0.421
gpmB
Phosphoglycerate mutase; COG0406 [G] Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.
       0.409
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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