Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0159Hypothetical protein. (377 aa)    
Predicted Functional Partners:
LSL_1483
Hypothetical membrane spanning protein.
  
     0.700
LSL_1525
Hypothetical membrane spanning protein.
  
     0.662
LSL_0158
COG0392 [S] Predicted integral membrane protein.
       0.572
LSL_0166
Hypothetical membrane spanning protein.
  
     0.568
LSL_0610
Hypothetical protein.
 
     0.529
LSL_1315
Transcriptional regulator, MarR family; COG0583 [K] Transcriptional regulator.
  
     0.494
aceF
COG0508 [C] Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
 
     0.461
LSL_1272
COG0344 [S] Predicted membrane protein.
  
     0.446
lplA
COG0095 [H] Lipoate-protein ligase A.
       0.436
acoA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
    0.412
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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