Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fruACOG1299 [G] Phosphotransferase system, fructose-specific IIC component. (651 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; COG1105 [G] Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 0.999
LSL_1619
PTS system, mannitol-specific IIA component; COG4668 [G] Mannitol/fructose-specific phosphotransferase system, IIA domain.
 
  
 0.993
ptsH
Phosphocarrier protein HPr; COG1925 [G] Phosphotransferase system, HPr-related proteins.
  
 
 0.988
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.985
LSL_0163
COG1349 [KG] Transcriptional regulators of sugar metabolism.
 
  
 0.984
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.983
fba
COG0191 [G] Fructose/tagatose bisphosphate aldolase.
  
 
 0.978
LSL_1461
Fructokinase; COG1940 [KG] Transcriptional regulator/sugar kinase.
  
 
 0.967
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.945
LSL_1628
COG3711 [K] Transcriptional antiterminator.
  
  
 0.893
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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