Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0182Hypothetical membrane spanning protein; COG0679 [R] Predicted permeases. (281 aa)    
Predicted Functional Partners:
LSL_0181
Conserved hypothetical protein; COG0344 [S] Predicted membrane protein.
 
    0.976
LSL_0180
Transcriptional regulator, LytR family; COG0583 [K] Transcriptional regulator.
       0.752
LSL_0183
Transcriptional regulators, LysR family; COG0583 [K] Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.536
LSL_0184
Phosphatase; COG0671 [I] Membrane-associated phospholipid phosphatase.
  
    0.508
wecD
Acetyltransferase, GNAT family.
       0.498
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.439
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.439
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
Server load: low (18%) [HD]