STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
baeS-2Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase. (383 aa)    
Predicted Functional Partners:
LSL_0205
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.985
LSL_0035
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.940
LSL_0522
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.882
LSL_1161
COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.873
LSL_1182
Alkaline phosphatase synthesis two-component response regulator phoP; COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.861
LSL_0861
Conserved hypothetical protein.
  
     0.543
LSL_0037
Hypothetical membrane spanning protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
 
  
 0.532
LSL_0204
Aminotransferase class I and II; COG1168 [E] Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
     
 0.495
LSL_1364
Conserved hypothetical protein; COG0517 [R] FOG: CBS domain.
 
     0.486
LSL_0038
COG0718 [S] Uncharacterized protein conserved in bacteria.
 
  
 0.480
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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