Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0210ABC transporter, ATP-binding protein; COG1136 [V] ABC-type antimicrobial peptide transport system, ATPase component. (661 aa)    
Predicted Functional Partners:
LSL_1460
Conserved hypothetical protein; COG0845 [M] Membrane-fusion protein.
 
 
 0.973
LSL_0211
Transcriptional regulator, TetR family; COG0583 [K] Transcriptional regulator.
   
 
 0.805
LSL_1374
ABC transporter permease protein; COG0577 [V] ABC-type antimicrobial peptide transport system, permease component.
 
 
 0.797
LSL_1458
ABC transporter permease protein; COG0577 [V] ABC-type antimicrobial peptide transport system, permease component.
 
 
0.792
LSL_1675
ABC transporter permease protein; COG0577 [V] ABC-type antimicrobial peptide transport system, permease component.
  
 
 0.767
LSL_0212
COG1132 [V] ABC-type multidrug transport system, ATPase and permease components.
     
0.751
baeS-3
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
  
 
 0.644
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 
 0.621
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.602
topB
DNA topoisomerase III; COG0550 [L] Topoisomerase IA.
     
 0.602
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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