| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LSL_0213 | LSL_0214 | LSL_0213 | LSL_0214 | ATPase associated with chromosome architecture/replication; COG2110 [R] Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | LemA protein; COG0011 [S] Uncharacterized conserved protein. | 0.526 |
| LSL_0213 | htpX | LSL_0213 | LSL_0215 | ATPase associated with chromosome architecture/replication; COG2110 [R] Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.517 |
| LSL_0214 | LSL_0213 | LSL_0214 | LSL_0213 | LemA protein; COG0011 [S] Uncharacterized conserved protein. | ATPase associated with chromosome architecture/replication; COG2110 [R] Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. | 0.526 |
| LSL_0214 | htpX | LSL_0214 | LSL_0215 | LemA protein; COG0011 [S] Uncharacterized conserved protein. | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.869 |
| aspS | hisS | LSL_0853 | LSL_0852 | Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | COG0124 [J] Histidyl-tRNA synthetase. | 0.995 |
| aspS | htpX | LSL_0853 | LSL_0215 | Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.537 |
| aspS | infB | LSL_0853 | LSL_0572 | Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.530 |
| atpC | htpX | LSL_0601 | LSL_0215 | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.724 |
| atpC | infB | LSL_0601 | LSL_0572 | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.783 |
| dnaJ | dnaK | LSL_0579 | LSL_0578 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | ftsH | LSL_0579 | LSL_1353 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.636 |
| dnaJ | grpE | LSL_0579 | LSL_0577 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.993 |
| dnaJ | htpX | LSL_0579 | LSL_0215 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.611 |
| dnaJ | infB | LSL_0579 | LSL_0572 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.450 |
| dnaK | dnaJ | LSL_0578 | LSL_0579 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.999 |
| dnaK | ftsH | LSL_0578 | LSL_1353 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.700 |
| dnaK | grpE | LSL_0578 | LSL_0577 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.999 |
| dnaK | hisS | LSL_0578 | LSL_0852 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | COG0124 [J] Histidyl-tRNA synthetase. | 0.420 |
| dnaK | htpX | LSL_0578 | LSL_0215 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Endopeptidase; COG0501 [O] Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. | 0.559 |
| dnaK | infB | LSL_0578 | LSL_0572 | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.728 |
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