Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
czcDCobalt-zinc-cadmium resistance protein; COG0053 [P] Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (341 aa)    
Predicted Functional Partners:
LSL_0650
Lactate/malate dehydrogenase.
  
    0.528
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
    0.528
LSL_1600
COG0039 [C] Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily.
  
    0.528
rep
COG0210 [L] Superfamily I DNA and RNA helicases.
       0.500
trpS
Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.483
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.439
recJ
COG0608 [L] Single-stranded DNA-specific exonuclease.
       0.439
eriC
COG0038 [P] Chloride channel protein EriC.
       0.436
mntH
Manganese transport protein; COG1914 [P] Mn2+ and Fe2+ transporters of the NRAMP family.
   
 
 0.432
LSL_1491
COG0344 [S] Predicted membrane protein.
 
   
 0.412
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
Server load: medium (52%) [HD]