Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0230VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. (77 aa)    
Predicted Functional Partners:
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
       0.717
tatD
DNase, TatD family; COG0084 [L] Mg-dependent DNase.
       0.702
metG
Methionyl-tRNA synthetase / Protein secretion chaperonin CsaA; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.618
rnmV1
Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family.
       0.584
LSL_0231
Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
       0.531
avtA
Aminotransferase; COG0436 [E] Aspartate/tyrosine/aromatic aminotransferase.
       0.514
LSL_1728
Phosphoesterase, DHH family protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
 
    0.507
purR
Pur operon repressor; COG0503 [F] Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
 
     0.487
LSL_1167
Central glycolytic genes regulator; COG2390 [K] Transcriptional regulator, contains sigma factor-related N-terminal domain.
  
     0.432
argR
Arginine repressor, argR; Regulates arginine biosynthesis genes.
       0.429
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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