| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LSL_0230 | LSL_0231 | LSL_0230 | LSL_0231 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold. | 0.531 |
| LSL_0230 | argR | LSL_0230 | LSL_0233 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | Arginine repressor, argR; Regulates arginine biosynthesis genes. | 0.429 |
| LSL_0230 | avtA | LSL_0230 | LSL_0232 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | Aminotransferase; COG0436 [E] Aspartate/tyrosine/aromatic aminotransferase. | 0.514 |
| LSL_0231 | LSL_0230 | LSL_0231 | LSL_0230 | Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold. | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.531 |
| LSL_0231 | argR | LSL_0231 | LSL_0233 | Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold. | Arginine repressor, argR; Regulates arginine biosynthesis genes. | 0.654 |
| LSL_0231 | avtA | LSL_0231 | LSL_0232 | Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold. | Aminotransferase; COG0436 [E] Aspartate/tyrosine/aromatic aminotransferase. | 0.746 |
| LSL_1082 | argR | LSL_1082 | LSL_0233 | COG2094 [L] 3-methyladenine DNA glycosylase. | Arginine repressor, argR; Regulates arginine biosynthesis genes. | 0.627 |
| argG | argH | LSL_0306 | LSL_0305 | COG0137 [E] Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | COG0165 [E] Argininosuccinate lyase. | 0.999 |
| argG | argR | LSL_0306 | LSL_0233 | COG0137 [E] Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Arginine repressor, argR; Regulates arginine biosynthesis genes. | 0.825 |
| argH | argG | LSL_0305 | LSL_0306 | COG0165 [E] Argininosuccinate lyase. | COG0137 [E] Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.999 |
| argH | argR | LSL_0305 | LSL_0233 | COG0165 [E] Argininosuccinate lyase. | Arginine repressor, argR; Regulates arginine biosynthesis genes. | 0.824 |
| argR | LSL_0230 | LSL_0233 | LSL_0230 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.429 |
| argR | LSL_0231 | LSL_0233 | LSL_0231 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold. | 0.654 |
| argR | LSL_1082 | LSL_0233 | LSL_1082 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | COG2094 [L] 3-methyladenine DNA glycosylase. | 0.627 |
| argR | argG | LSL_0233 | LSL_0306 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | COG0137 [E] Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.825 |
| argR | argH | LSL_0233 | LSL_0305 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | COG0165 [E] Argininosuccinate lyase. | 0.824 |
| argR | argS | LSL_0233 | LSL_0677 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | COG0018 [J] Arginyl-tRNA synthetase. | 0.773 |
| argR | avtA | LSL_0233 | LSL_0232 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | Aminotransferase; COG0436 [E] Aspartate/tyrosine/aromatic aminotransferase. | 0.658 |
| argR | birA | LSL_0233 | LSL_0325 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.416 |
| argR | thyA | LSL_0233 | LSL_0708 | Arginine repressor, argR; Regulates arginine biosynthesis genes. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.440 |