node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSL_0230 | ispE | LSL_0230 | LSL_0234 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.416 |
LSL_0230 | ksgA | LSL_0230 | LSL_0229 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.748 |
LSL_0230 | tatD | LSL_0230 | LSL_0227 | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | DNase, TatD family; COG0084 [L] Mg-dependent DNase. | 0.735 |
LSL_1359 | ispE | LSL_1359 | LSL_0234 | COG2244 [R] Membrane protein involved in the export of O-antigen and teichoic acid. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.568 |
LSL_1359 | ksgA | LSL_1359 | LSL_0229 | COG2244 [R] Membrane protein involved in the export of O-antigen and teichoic acid. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.474 |
amtB | guaA-3 | LSL_0235 | LSL_1537 | Ammonium transporter; COG0004 [P] Ammonia permease. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.462 |
amtB | ispE | LSL_0235 | LSL_0234 | Ammonium transporter; COG0004 [P] Ammonia permease. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.499 |
dxs | ispE | LSL_0209 | LSL_0234 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.571 |
dxs | polA | LSL_0209 | LSL_0488 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.420 |
guaA-3 | amtB | LSL_1537 | LSL_0235 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ammonium transporter; COG0004 [P] Ammonia permease. | 0.462 |
guaA-3 | ispE | LSL_1537 | LSL_0234 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.470 |
guaA-3 | ksgA | LSL_1537 | LSL_0229 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.604 |
guaA-3 | metK | LSL_1537 | LSL_0441 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.707 |
guaA-3 | polA | LSL_1537 | LSL_0488 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.829 |
ispE | LSL_0230 | LSL_0234 | LSL_0230 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | VEG protein; COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.416 |
ispE | LSL_1359 | LSL_0234 | LSL_1359 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | COG2244 [R] Membrane protein involved in the export of O-antigen and teichoic acid. | 0.568 |
ispE | amtB | LSL_0234 | LSL_0235 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Ammonium transporter; COG0004 [P] Ammonia permease. | 0.499 |
ispE | dxs | LSL_0234 | LSL_0209 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.571 |
ispE | guaA-3 | LSL_0234 | LSL_1537 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.470 |
ispE | ksgA | LSL_0234 | LSL_0229 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.960 |