glmU protein (Lactobacillus salivarius) - STRING interaction network

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glmU

Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...] (469 aa)

Predicted Functional Partners:

glmM

0.997

prsA

0.965

glmS

0.963

murC

0.960

murA

0.937

murA-2

0.937

galU

0.933

wecB

0.927

ugd

0.890

purR

0.888

Your Current Organism:

Lactobacillus salivarius

NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
galU	glmM	LSL_1268	LSL_1144	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	0.617
galU	glmS	LSL_1268	LSL_1627	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.590
galU	glmU	LSL_1268	LSL_0317	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...]	0.933
galU	murA	LSL_1268	LSL_0345	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.834
galU	murA-2	LSL_1268	LSL_0603	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.834
galU	ugd	LSL_1268	LSL_0979	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	COG1004 [M] Predicted UDP-glucose 6-dehydrogenase.	0.976
galU	wecB	LSL_1268	LSL_1276	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	COG0381 [M] UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.884
glmM	galU	LSL_1144	LSL_1268	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	0.617
glmM	glmS	LSL_1144	LSL_1627	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.983
glmM	glmU	LSL_1144	LSL_0317	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...]	0.997
glmM	murA	LSL_1144	LSL_0345	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.515
glmM	murA-2	LSL_1144	LSL_0603	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.544
glmM	murC	LSL_1144	LSL_0485	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.557
glmM	ugd	LSL_1144	LSL_0979	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	COG1004 [M] Predicted UDP-glucose 6-dehydrogenase.	0.426
glmS	galU	LSL_1627	LSL_1268	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	0.590
glmS	glmM	LSL_1627	LSL_1144	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	0.983
glmS	glmU	LSL_1627	LSL_0317	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...]	0.963
glmS	ugd	LSL_1627	LSL_0979	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	COG1004 [M] Predicted UDP-glucose 6-dehydrogenase.	0.471
glmU	galU	LSL_0317	LSL_1268	Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...]	UTP--glucose-1-phosphate uridylyltransferase; COG1210 [M] UDP-glucose pyrophosphorylase.	0.933
glmU	glmM	LSL_0317	LSL_1144	Glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...]	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	0.997

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