Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0338Hydrolase; COG1078 [R] HD superfamily phosphohydrolases. (451 aa)    
Predicted Functional Partners:
rpoE
DNA-directed RNA polymerase delta chain; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
 
     0.817
LSL_0337
Hydrolase, HAD superfamily; COG0561 [R] Predicted hydrolases of the HAD superfamily.
      0.777
LSL_0340
Conserved hypothetical protein.
     
 0.637
LSL_0034
Hydrolase, HAD superfamily; COG0561 [R] Predicted hydrolases of the HAD superfamily.
    
 0.600
LSL_0500
GTP-binding protein; COG1160 [R] Predicted GTPases.
  
     0.579
LSL_0336
Hypothetical membrane spanning protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.565
guaA-2
COG0518 [F] GMP synthase - Glutamine amidotransferase domain; glutamine-hydrolyzing.
       0.499
LSL_0882
ABC transporter, ATP-binding protein; COG1101 [R] ABC-type uncharacterized transport system, ATPase component.
   
    0.485
LSL_0514
COG1428 [F] Deoxynucleoside kinases.
    
   0.456
LSL_1642
COG1428 [F] Deoxynucleoside kinases.
    
   0.456
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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