Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0362COG2404 [R] Predicted phosphohydrolase (DHH superfamily). (363 aa)    
Predicted Functional Partners:
LSL_0231
Conserved hypothetical protein; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
  
     0.756
LSL_1638
DNA-entry nuclease.
  
     0.740
LSL_0361
COG0011 [S] Uncharacterized conserved protein.
       0.732
LSL_0364
Conserved hypothetical protein.
 
     0.723
LSL_1037
Conserved hypothetical protein; COG0639 [T] Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.
  
     0.693
LSL_1321
COG4086 [S] Predicted secreted protein.
  
     0.676
LSL_1546
Hypothetical exported protein; COG5263 [R] FOG: Glucan-binding domain (YG repeat).
  
    0.607
LSL_0058
Hypothetical protein.
  
     0.584
LSL_1272
COG0344 [S] Predicted membrane protein.
  
     0.582
LSL_0070
COG2738 [R] Predicted Zn-dependent protease.
  
     0.572
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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