Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmAtRNA (Uracil-5-) -methyltransferase; COG2265 [J] SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (459 aa)    
Predicted Functional Partners:
recX
Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
  
    0.696
LSL_0370
Conserved hypothetical protein; COG3557 [J] Uncharacterized domain/protein associated with RNAses G and E; Belongs to the UPF0374 family.
       0.572
gpsA
COG0240 [C] Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
    0.433
trmB
tRNA (m(7)G46) methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.432
LSL_0615
16S rRNA m(5)C 967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.431
pheT
COG0072 [J] Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.428
LSL_0367
Sigma-70 factor family protein.
       0.422
guaA-3
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.414
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
       0.408
lysS
COG1190 [J] Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.405
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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