| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| prfB | prfC | LSL_1185 | LSL_0374 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 0.778 |
| prfB | rplI | LSL_1185 | LSL_1727 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.903 |
| prfB | rplL | LSL_1185 | LSL_1237 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.904 |
| prfB | rplM | LSL_1185 | LSL_1403 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.915 |
| prfB | rplQ | LSL_1185 | LSL_1408 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | COG0203 [J] Ribosomal protein L17. | 0.914 |
| prfB | rplS | LSL_1185 | LSL_0636 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.944 |
| prfB | rplT | LSL_1185 | LSL_0497 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.919 |
| prfB | rpmA | LSL_1185 | LSL_0954 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | COG0211 [J] Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.958 |
| prfB | rpmF | LSL_1185 | LSL_0507 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | COG0333 [J] Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.891 |
| prfB | rpmJ | LSL_1185 | LSL_1412 | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | COG0257 [J] Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.879 |
| prfC | prfB | LSL_0374 | LSL_1185 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | Bacterial Peptide Chain Release Factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.778 |
| prfC | rplI | LSL_0374 | LSL_1727 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.749 |
| prfC | rplL | LSL_0374 | LSL_1237 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.780 |
| prfC | rplM | LSL_0374 | LSL_1403 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.738 |
| prfC | rplQ | LSL_0374 | LSL_1408 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | COG0203 [J] Ribosomal protein L17. | 0.733 |
| prfC | rplS | LSL_0374 | LSL_0636 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.785 |
| prfC | rplT | LSL_0374 | LSL_0497 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.789 |
| prfC | rpmA | LSL_0374 | LSL_0954 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | COG0211 [J] Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.821 |
| prfC | rpmF | LSL_0374 | LSL_0507 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | COG0333 [J] Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.739 |
| prfC | rpmJ | LSL_0374 | LSL_1412 | Bacterial Peptide Chain Release Factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | COG0257 [J] Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.744 |
STRING v12.5 is now available!
