Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacZCOG3250 [G] Beta-galactosidase/beta-glucuronidase. (1007 aa)    
Predicted Functional Partners:
galA
COG3345 [G] Alpha-galactosidase.
 
 
 0.984
galM-2
Aldose 1-epimerase; Catalyzes the interconversion of alpha and beta anomers of maltose.
 
 
 0.960
galM
Aldose 1-epimerase; COG2017 [G] Galactose mutarotase and related enzymes.
 
 
 0.959
LSL_0552
Glucokinase; COG1940 [KG] Transcriptional regulator/sugar kinase.
    
 0.922
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.819
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.718
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.718
pckA
COG1866 [C] Phosphoenolpyruvate carboxykinase (ATP).
   
  
 0.561
aes
Endo-1,4-beta-xylanase; COG0657 [I] Esterase/lipase.
 
 
 0.550
galT
COG4468 [G] Galactose-1-phosphate uridyltransferase.
 
   
 0.547
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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