Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepQCOG0006 [E] Xaa-Pro aminopeptidase. (367 aa)    
Predicted Functional Partners:
pepD
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
 
 0.811
ccpA
Catabolite control protein A; COG1522 [K] Transcriptional regulators.
  
 
 0.756
pepX
Xaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
  
   
 0.721
pepO
COG3590 [O] Predicted metalloendopeptidase.
   
  
 0.717
LSL_0447
Xaa-His dipeptidase; COG0624 [E] Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
   
 
 0.659
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
  
 0.636
LSL_0398
COG1164 [E] Oligoendopeptidase F.
      
 0.614
LSL_1265
Di-/tripeptide transporter; COG3104 [E] Dipeptide/tripeptide permease.
  
  
 0.494
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.486
LSL_1113
Phosphoesterase, DHH family protein; COG0618 [R] Exopolyphosphatase-related proteins.
 
     0.469
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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