Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBCOG0492 [O] Thioredoxin reductase. (341 aa)    
Predicted Functional Partners:
trxA-2
Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.710
trxA-3
Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.710
LSL_0440
Polyribonucleotide nucleotidyltransferase; COG1098 [J] Predicted RNA binding protein (contains ribosomal protein S1 domain).
       0.628
dedA
DedA family protein; COG0586 [S] Uncharacterized membrane-associated protein.
       0.623
trxA
Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins.
  
 
 0.606
metG
Methionyl-tRNA synthetase / Protein secretion chaperonin CsaA; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
 
 0.596
grxC
COG0695 [O] Glutaredoxin and related proteins.
   
 
 0.451
lpd
COG1249 [C] Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.422
LSL_1329
Pyridine nucleotide-disulphide oxidoreductase family protein; COG1249 [C] Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.422
phoH
PhoH protein; COG1702 [T] Phosphate starvation-inducible protein PhoH, predicted ATPase.
   
  
 0.401
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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