| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LSL_0467 | glpF-2 | LSL_0467 | LSL_0466 | COG0517 [R] FOG: CBS domain. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.484 |
| LSL_0471 | dnaJ | LSL_0471 | LSL_0579 | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.428 |
| LSL_0471 | glpF-2 | LSL_0471 | LSL_0466 | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.482 |
| LSL_0471 | scrA | LSL_0471 | LSL_0066 | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.435 |
| LSL_0616 | dnaJ | LSL_0616 | LSL_0579 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.734 |
| LSL_0616 | glpF-2 | LSL_0616 | LSL_0466 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.482 |
| LSL_0616 | ppiB | LSL_0616 | LSL_0055 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.697 |
| LSL_0616 | spoVK | LSL_0616 | LSL_0329 | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | COG0464 [O] ATPases of the AAA+ class. | 0.725 |
| dnaJ | LSL_0471 | LSL_0579 | LSL_0471 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | 0.428 |
| dnaJ | LSL_0616 | LSL_0579 | LSL_0616 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Protein phosphatase 2C; COG0631 [T] Serine/threonine protein phosphatase. | 0.734 |
| dnaJ | glpF-2 | LSL_0579 | LSL_0466 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.544 |
| dnaJ | glpK | LSL_0579 | LSL_0110 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.530 |
| dnaJ | ppiB | LSL_0579 | LSL_0055 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.786 |
| dnaJ | spoVK | LSL_0579 | LSL_0329 | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | COG0464 [O] ATPases of the AAA+ class. | 0.755 |
| fruA | glpF-2 | LSL_0165 | LSL_0466 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.621 |
| fruA | glpK | LSL_0165 | LSL_0110 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.677 |
| fruA | glpO | LSL_0165 | LSL_0111 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | Alpha-glycerophosphate oxidase; COG0240 [C] Glycerol-3-phosphate dehydrogenase. | 0.500 |
| fruA | scrA | LSL_0165 | LSL_0066 | COG1299 [G] Phosphotransferase system, fructose-specific IIC component. | PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.983 |
| glpF-2 | LSL_0467 | LSL_0466 | LSL_0467 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | COG0517 [R] FOG: CBS domain. | 0.484 |
| glpF-2 | LSL_0471 | LSL_0466 | LSL_0471 | COG0580 [G] Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Transcription regulator, Crp family; COG0583 [K] Transcriptional regulator. | 0.482 |